Top 11 Cinematic Experiments Gone Wrong

The road to hell is paved with good intentions.” Truer words were never spoken. So when someone decides to construct a body from cadaver parts and reanimate it with a lightning bolt, or surgically connect three people with one gastroenterological tract, they always hope for the best. Unfortunately, that’s not usually the result.

Which leads us to our latest list of the best and the brightest. In honor of the DVD/Blu-ray release of The Apparition on November 27th, we bring out our list of Top 11 films featuring Experiments Gone Wrong.

As always, we’ve got to give a shout out to a few honorable mentions. Who would think that things would go wrong with keeping a cryogenically frozen Jason Voorhees, as in Jason X? Surprisingly, things went bad there. The splicing of DNA from different animals sounds like a brilliant idea, no? Splice proved that was a wonky idea as well. And certainly the Umbrella Corporation is responsible for making some really poor managerial decisions that resulted in the release of the T-Virus in Resident Evil.

And now, the Top 11 Experiments Gone Wrong.

Frankenstein (1931)

We might as well start this list with the most obvious entry. Frankenstein is the granddaddy of the experiment gone wrong tale. James Whale’s legendary adaptation of Mary Shelley’s vision is obviously the blueprint for stories of science gone awry. You would think that sewing a bunch of body parts together and then running a lightning bolt through the creature would generate happy times, but alas, this was not the case. Frankenstein is the original and quintessential example of experiments gone wrong. Boris Karloff delivers what can only be described as a monumental performance in a film that is as impactful today as it was when it was released over 80 years ago..

MORE Top 11 Experiments Gone Wrong in Horror on the NEXT page!

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Scott Hallam

We all go a little mad sometimes...haven't you?

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  • nazo

    I thought this was going to be about the other kind of cinematic experiments gone wrong, the kind usually involving someone like Uwe Boll.

    • Hakk Wylde

      BWAHAHAHAHA! Nice.
      GREAT idea for a list! }:)

  • Hakk Wylde

    Wicked list! I like HUMAN CENTIPEDE in there…definitely a very important this-generation dangers of extreme science movie. I would only add GOJIRA }:)

  • Terminal

    Take out Human Centipede and you have a wonderful list there. You could replace it with Colossus the Forbin Project, or Godzilla, or Deep Blue Sea, hell, even Night of the Living Dead. Great list though!

    • Doctor Gash

      Thanks Terminal! I tried to mix it up a little bit. Of course there were some entries that were must-haves, but I think we snuck a couple fresh ones in there. And I’m a sucker for the ‘pede!